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产品目录

Lactadherin/MFGE8抗体图片
产品货号:
Z34550
中文名称:
Lactadherin/MFGE8抗体
英文名称:
Anti-Lactadherin/MFGE8 Antibody (Clone#OTI7A4)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Lactadherin/MFGE8 Antibody (Clone#OTI7A4)
指标别名BA46;Breast epithelial antigen BA46;EDIL1;HMFG;hP47;HsT19888;Lactadherin;MFG E8;MFGE8;MFG-E8;MFGM;Milk fat globule EGF factor 8;OAcGD3S;SED1;SPAG10
克隆性Monoclonal
检验物种human
应用范围WB,IHC
基因名称MFGE8
克隆号OTI7A4
抗体来源Mouse
抗体类型IgG1
免疫原Full length human recombinant protein of human MFGE8 (NP_005919) produced in HEK293T cell.
实际分子量42.9KD
成分PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide.
纯化方式Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度500μg/mL
产品形态溶液
保存条件Stable for 12 months from date of receipt.Store at -20℃ as received.
背景资料MFGE8(Milk Fat Globule-Egf Factor 8),also called as Lactadherin or SED1,is a protein which in humans is encoded by the MFGE8 gene.Mfge8 is secreted protein found in vertebrates,including mammals as well as birds.By fluorescence in situ hybridization,Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25.Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes.MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine.MFGE8,when engaged by phospholipids,bound to cells via its RGD motif.It bound particularly strongly to cells expressing alpha-V-beta-3 integrin.Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice.Using a wound-healing assay,they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.
Uniprot IDP21956
基因名全称milk fat globule EGF and factor V/VIII domain containing
蛋白名全称Lactadherin
推荐稀释比
Western blot (WB) 1:2000
Immunohistochemistry in paraffin section (IHC) 1:500

相关搜索:Lactadherin/MFGE8抗体Lactadherin抗体MFGE8单抗Anti-Lactadherin/MFGE8 Antibody (Clone#OTI7A4)
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